POXVIRUS INTERACTIONS WITH THE HOST UBIQUITIN SYSTEM

Poxvirus Interactions with the Host Ubiquitin System

The ubiquitin system has emerged as a master regulator of many, if not all, cellular functions.With its large repertoire of conjugating and ligating enzymes, the ubiquitin system holds a unique mechanism to provide selectivity and specificity in manipulating protein function.As intracellular parasites viruses have evolved to modulate the cellular e

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Familial reactive perforating collagenosis

Background: Reactive perforating collagenosis (RPC) is one of the rare forms of transepidermal elimination in which genetically altered collagen is extruded from the epidermis.This disease usually starts in early childhood as trigon decal asymptomatic umbilicated papules on extremities, and the lesions become more conspicuous with age.Aims: The obj

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Thymol polymeric nanoparticle synthesis and its effects on the toxicity of high glucose on OEC cells: involvement of growth factors and integrin-linked kinase

Elahe Karimi,1,2 Shahryar Abbasi,1,3 Naser Abbasi2,41Department of Chemistry, Ilam Branch, Islamic Azad University, Ilam, Iran; 2Biotechnology and Medicinal Plants Research Center, Ilam University of Medical Sciences, Ilam, Iran; 3Department of Chemistry, Faculty of Science, Ilam University, Ilam, Iran; 4Department of Pharmacology, Medica

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Weather Information Acquisition and Health Significance during Extreme Cold Weather in a Subtropical City: A Cross-sectional Survey in Hong Kong

Abstract Health and nucleus ball toy disaster risk reduction are important and necessary components in building a smart city, especially when climate change may increase the frequency of extreme temperatures and the health risks of urban dwellers.However, limited knowledge is available about the best way to disseminate weather warnings and health p

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